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Restless Leg SyndromeModerate renal impairmentCrCl 30 to 50 mL/minNo dosage adjustment is necessary Severe renal impairment without regular dialysisNo data available.
LevodopaciprofloxacinCiprofluvoxamineLuvoxmetoclopramideReglanomeprazolePriloseca medication used to treat nausea and vomiting or mental illnesssuch as chlorpromazineThorazinefluphenazineProlixinmesoridazineSerentilperphenazineTrilafonthioridazineMellarilpromazineSparinetrifluoperazineStelazinethiothixeneNavaneor haloperidolHaldolor an estrogen such as PremarinPremproEstratestOgenEstradermClimaraVivelleestradioland others.
Other medications can affect the removal of ropinirole from your bodywhich may affect how ropinirole worksExamples include cimetidinefluvoxaminemexiletineomeprazolerifampinamong others.
Uncommon0.1to 1Sudden onset of sleepexcessive daytime somnolence.
The recommended adult starting dose for RLS is 0.25 mg once daily 1 to 3 hours before bedtimeAfter 2 daysif necessarythe dose can be increased to 0.5 mg once dailyand to 1 mg once daily at the end of the first week of dosingthen as shown in Table 2 as needed to achieve efficacyTitration should be based on individual patient therapeutic response and tolerabilityup to a maximum recommended dose of 4 mg dailyFor RLSthe safety and effectiveness of doses greater than 4 mg once daily have not been established.
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