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A few cases of rashurticariaor bronchospasmespecially in patients with a history of asthmaRarelyangioneurotic edemaincluding glossal or laryngeal edema.
Care should be exercised in administering metoclopramide to neonates since prolonged clearance may produce excessive serum concentrationssee CLINICAL PHARMACOLOGYPharmacokineticsIn additionneonates have reduced levels of NADH-cytochrome b 5 reductase whichin combination with the aforementioned pharmacokinetic factorsmake neonates more susceptible to methemoglobinemiasee OVERDOSE
Transient flushing of the face and upper bodywithout alterations in vital signsfollowing high doses intravenously.
Experience with esophageal erosions and ulcerations is limitedbut healing has thus far been documented in one controlled trial using q.i.dtherapy at 15 mg/doseand this regimen should be used when lesions are presentso long as it is toleratedsee ADVERSE REACTIONSBecause of the poor correlation between symptoms and endoscopic appearance of the esophagustherapy directed at esophageal lesions is best guided by endoscopic evaluation.
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