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Claithomycin : Atovastatin AUC was signiicantly incasd with concomitant administation atovastatin 80 mg with claithomycin (500 mg twic daily) compad tthat atovastatin alon. Tho, in patints taking claithomycin, caution should b usd whn th dos atovastatin xcds 20 mg.
Gmibozil: Du tan incasd isk myopathy/habdomyolysis whn HMG-CoA ductas inhibitos a co-administd with gmibozil, concomitant administation ATOLIP CV with gmibozil should b avoidd.
Non-stoidal Anti-inlammatoy Agnts (NSAIDs): Co-administation ATOLIP CV and NSAIDs incass th isk gastointstinal blding and hnc should b co-administd with caution. Although aspiin did not modiy th clopidogl-mdiatd inhibition ADP-inducd platlt agggation, clopidogl potntiatd th ct aspiin on collagn-inducd platlt agggation. Howv, concomitant administation 500 mg aspiin twic a day on day did not signiicantly incas th polongation blding tim inducd by clopidogl intak. A phamacodynamic intaction btwn ATOLIP CV and aspiin is possibl, lading tincasd isk blding. Tho, concomitant us should b undtakn with caution. Howv, clopidogl and aspiin hav bn administd togth up ton ya.
Atovastatin ducs total-C, LDL-C and apB in patints with homozygous and htozygous H, nonamilial oms hypcholstolmia and mixd dyslipidmia. Atovastatin alsducs VLDL-C and TG and poducs vaiabl incass in HDL-C and apA-1. Atovastatin ducs total-C, LDL-C, VLDL-C, apB, TG and non-HDL-C and incass HDL-C in patints with isolatd hyptiglycidmia. Atovastatin ducs IDL cholstol (IDL-C) in patints with dysbtalipopotinmia.
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atorlip-f fenofibrate demonstrated a non-significant 11 relative reduction in the primary outcome of coronary heart disease events hazard ratio hr 0.