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Gnal: An incas in acut attacks gout has bn potd duing th aly stags administation ZYLOPIM (allopuinol) , vn whn nomal subnomal sum uic acid lvls hav bn attaind. Accodingly, maintnanc doss colchicin gnally should b givn pophylactically whn ZYLOPIM (allopuinol) is bgun. In addition, it is commndd that th patint stat with a low dos ZYLOPIM (allopuinol) (100 mg daily) and incas at wkly intvals by 100 mg until a sum uic acid lvl 6 mg/dL lss is attaind but without xcding th maximum commndd dos (800 mg p day). Th us colchicin anti-inlammatoy agnts may b quid tsuppss gouty attacks in som cass. Th attacks usually bcom shot and lss sv at sval months thapy. Th mobilization uats om tissu dposits which caus luctuations in th sum uic acid lvls may b a possibl xplanation ths pisods. vn with adquat thapy with ZYLOPIM (allopuinol) , it may qui sval months tdplt th uic acid pool suicintly tachiv contol th acut attacks.
Allopuinol is usd ttat gout, high lvls uic acid in th body causd by ctain canc mdications, and kidny stons. Allopuinol is in a class mdications calld xanthin oxidas inhibitos. It woks by ducing th poduction uic acid in th body. High lvls uic acid may caus gout attacks kidny stons. Allopuinol is usd tpvnt gout attacks, not ttat thm onc thy occu.
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