Metformin is negligibly bound to plasma proteins, in contrast to sulfonylureas, which are more than 90 protein bound.
Information about Metformin.
It’s best to take metformin tablets with a meal to reduce the side effectsSwallow your metformin tablets whole with a glass of waterDo not chew them.
Over timepeople who have diabetes and high blood sugar can develop serious or life-threatening complicationsincluding heart diseasestrokekidney problemsnerve damageand eye problemsTaking medication(smaking lifestyle changese.gdietexercisequitting smokingand regularly checking your blood sugar may help to manage your diabetes and improve your healthThis therapy may also decrease your chances of having a heart attackstrokeor other diabetes-related complications such as kidney failurenerve damagenumbcold legs or feetdecreased sexual ability in men and womeneye problemsincluding changes or loss of visionor gum diseaseYour doctor and other healthcare providers will talk to you about the best way to manage your diabetes.
Keep all appointments with your doctor and the laboratoryYour doctor will order certain tests before and during treatment to check how well your kidneys are working and your body’s response to metforminTalk to your doctor about the risk(sof taking metformin.
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the contraindications in using metformin include liver disease, alcoholism, compromised renal function, hypoxic conditions, and moderate to severe infections.