I have been taking400mg of plaquenil for 4 months.
Information about Plaquenil.
The 4-aminoquinoline compounds are very rapidly and completely absorbed after ingestionand in accidental overdosageor rarely with lower doses in hypersensitive patientstoxic symptoms may occur within 30 minutesThe symptoms of overdosage may include headachedrowsinessvisual disturbancescardiovascular collapseconvulsionshypokalemiarhythm and conduction disorders including QT prolongationtorsade de pointeventricular tachycardia and ventricular fibrillationfollowed by sudden potentially fatal respiratory and cardiac arrestImmediate medical attention is requiredas these effects may appear shortly after the overdoseTreatment is symptomatic and must be prompt with immediate evacuation of the stomach by emesisat homebefore transportation to the hospitalor gastric lavage until the stomach is completely emptiedIf finely powderedactivated charcoal is introduced by the stomach tubeafter lavageand within 30 minutes after ingestion of the tabletsit may inhibit further intestinal absorption of the drugTo be effectivethe dose of activated charcoal should be at least five times the estimated dose of hydroxychloroquine ingestedConvulsionsif presentshould be controlled before attempting gastric lavageIf due to cerebral stimulationcautious administration of an ultrashort-acting barbiturate may be tried butif due to anoxiait should be corrected by oxygen administrationartificial respiration orin shock with hypotensionby vasopressor therapyBecause of the importance of supporting respirationtracheal intubation or tracheostomyfollowed by gastric lavagemay also be necessaryExchange transfusions have been used to reduce the level of 4-aminoquinoline drug in the blood.
In adults400 mg310 mg baseon exactly the same day of each weekIn infants and childrenthe weekly suppressive dosage is 5 mgcalculated as baseper kg of body weightbut should not exceed the adult dose regardless of weight.
Not for treating complicated malariaNot effective against chloroquineor hydroxychloroquine-resistant strainsNot for preventing relapses of Pvivax or PovaleNot for treatment and prophylaxis in chloroquine-resistant areas.
Bleaching of hairalopeciapruritusskin and mucosal pigmentationphotosensitivityand skin eruptionsurticarialmorbilliformlichenoidmaculopapularpurpuricerythema multiformeerythema annulare centrifugumStevens-Johnson syndrometoxic epidermal necrolysisacute generalized exanthematous pustulosisand exfoliative dermatitis
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to make sure plaquenil is safe for you, tell your doctor if you have any of these conditions .