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The earliest and most frequent manifestation of digoxin toxicity in infants and children is the appearance of cardiac arrhythmiasincluding sinus bradycardiaIn childrenthe use of digoxin may produce any arrhythmiaThe most common are conduction disturbances or supraventricular tachyarrhythmiassuch as atrial tachycardiawith or without blockand junctionalnodaltachycardiaVentricular arrhythmias are less commonSinus bradycardia may be a sign of impending digoxin intoxicationespecially in infantseven in the absence of first-degree heart blockAny arrhythmias or alteration in cardiac conduction that develops in a child taking digoxin should initially be assumed to be a consequence of digoxin intoxication.
Like all medicinesthis medicine can cause side effectsalthough not everybody gets them.
Jay WMarksMDis a board-certified internist and gastroenterologistHe graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.
Many digoxin side effects are dose dependent and happen when blood levels are over the narrow therapeutic rangeThereforedigoxin side effects can be avoided by keeping blood levels within the therapeutic levelSerious side effects associated with digoxin include.
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