A weight gain can be a common side effect of the selective serotonin reuptake inhibitors ssris , the class of drugs that includes lexapro escitalopram .
Information about Lexapro.
Combined administration of racemic citalopram40 mg/day for 14 daysand carbamazepinetitrated to 400 mg/day for 35 daysdid not significantly affect the pharmacokinetics of carbamazepinea CYP3A4 substrateAlthough trough citalopram plasma levels were unaffectedgiven the enzyme-inducing properties of carbamazepinethe possibility that carbamazepine might increase the clearance of escitalopram should be considered if the two drugs are coadministered.
Escitalopram is metabolized to S-DCT and S-didemethylcitalopramS-DDCTIn humansunchanged escitalopram is the predominant compound in plasmaAt steady statethe concentration of the escitalopram metabolite S-DCT in plasma is approximately one-third that of escitalopramThe level of S-DDCT was not detectable in most subjectsIn vitro studies show that escitalopram is at least 7 and 27 times more potent than S-DCT and S-DDCTrespectivelyin the inhibition of serotonin reuptakesuggesting that the metabolites of escitalopram do not contribute significantly to the antidepressant actions of escitalopramS-DCT and S-DDCT also have no or very low affinity for serotonergic5-HT 1-7or other receptors including alphaand beta-adrenergicdopamineD 1-5histamineH 1-3muscarinicM 1-5and benzodiazepine receptorsS-DCT and S-DDCT also do not bind to various ion channels including NaKCl and Cachannels.
Lexapro has not been systematically evaluated in patients with a recent history of myocardial infarction or unstable heart diseasePatients with these diagnoses were generally excluded from clinical studies during the product’s premarketing testing.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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any other antidepressants such as amitriptyline elavil, vanatrip, limbitrol , escitalopram lexapro , imipramine tofranil , sertraline zoloft , and others, alprazolam xanax , clopidogrel plavix , clozapine clozaril, fazaclo , flecainide tambocor , haloperidol haldol , nebivolol bystolic , vinblastine velban , a blood thinner such as warfarin coumadin, jantoven , migraine headache medicine such as almotriptan axert , frovatriptan frova , sumatriptan imitrex, treximet , naratriptan amerge , rizatriptan maxalt , or zolmitriptan zomig , or seizure medication such as phenytoin dilantin or carbamazepine carbatrol, equetro, tegretol .