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How are patients typically monitoredPatients will usually have scheduled meetings with their healthcare provider while they are being treated with cyclophosphamideTypicallyblood will be drawn to check levels of blood cells and to monitor functions of some organ systemssuch as the kidneys or liverPatients may also undergo physical examinationsscans or other measures to assess side effects and response to therapy.
Before using this medicationtell your doctor or pharmacist your medical historyespecially ofliver diseasekidney diseasesurgery to remove your adrenal glands.
This is not a complete list of possible side effectsIf you notice other effects not listed abovecontact your doctor or pharmacist.
Leukopenia occurs in patients treated with cyclophosphamideis related to the dose of drugand can be used as a dosage guideLeukopenia of less than 2000 cells/mm 3 develops commonly in patients treated with an initial loading dose of the drugand less frequently in patients maintained on smaller dosesThe degree of neutropenia is particularly important because it correlates with a reduction in resistance to infectionsFever without documented infection has been reported in neutropenic patients.
Malignant lymphomasStages III and IV of the Ann Arbor staging systemHodgkin’s diseaselymphocytic lymphomanodular or diffusemixed-cell type lymphomahistiocytic lymphomaBurkitt’s lymphoma multiple myeloma leukemiaschronic lymphocytic leukemiachronic granulocytic leukemiait is usually ineffective in acute blastic crisisacute myelogenous and monocytic leukemiaacute lymphoblasticstem-cellleukemiacyclophosphamide given during remission is effective in prolonging its durationmycosis fungoidesadvanced diseaseneuroblastomadisseminated diseaseadenocarcinoma of the ovary retinoblastoma carcinoma of the breast.
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