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Table 1Adult Recommended Dosage Regimen for Prevention of Nausea and Vomiting.
Otherless than 2Anaphylaxisbronchospasmtachycardiaanginahypokalemiaelectrocardiographic alterationsvascular occlusive eventsand grand mal seizuresExcept for bronchospasm and anaphylaxisthe relationship to ZOFRAN is unclear.
Ondansetron is used to prevent nausea and vomiting that may be caused by surgery or by medicine to treat cancerchemotherapy or radiation
Although no pharmacokinetic drug interaction between ondansetron and tramadol has been observeddata from 2 small trials indicate that when used togetherZOFRAN may increase patient-controlled administration of tramadolMonitor patients to ensure adequate pain control when ondansetron is administered with tramadol.
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physicians knowingly prescribed zofran to pregnant women.