The metabolites include 6-, 7-, and 8-hydroxylated-etodolac and etodolac glucuronide.
Information about Etodolac.
References are publications that support the biological activity of the product.
Oedemahypertension and cardiac failurehave been reported in association with NSAID treatmentClinical trial and epidemiological data suggest that use of some NSAIDsparticularly at high doses and in long term treatmentmay be associated with an increased risk of arterial thrombotic eventsfor example myocardial infarction or strokesee section 4.4
The clinical benefit of preferential COX-2 inhibition over COX-1 has yet to be proven.
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