In a trial comparing chronic dosing with wellbutrin sr 150 mg twice daily to bupropion immediate-release formulation 100 mg 3 times daily, the steady state cmax for bupropion after wellbutrin sr administration was approximately 85 of those achieved after bupropion immediate-release formulation administration.
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Report any new or worsening symptoms to your doctorsuch asmood or behavior changesanxietypanic attackstrouble sleepingor if you feel impulsiveirritableagitatedhostileaggressiverestlesshyperactivementally or physicallymore depressedor have thoughts about suicide or hurting yourself.
Seizure risk is dose-relatedcan minimize risk by limiting daily dose to 522 mg and gradually increasing dosediscontinue permanently in patients who experience seizures.
Risk of mydriasismay trigger angle closure attack in patients with angle closure glaucoma with anatomically narrow angles without a patent iridectomyuse caution.
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many gps associated serious side-effects with bupropion which was negatively associated with gps intentions to prescribe bupropion.