One study involving 51 menopausal women published in the 2012 issue of ayurveda, showed that daily intake of ashwagandha supplement resulted in a significant improvement in symptoms of menopause syndrome, such as hot flashes, mood swings and anxiety.
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Micoaay analysis vald that ashwagandha psss poinlammatoy gn xpssion, including IL-6, IL-1?, IL-8, Hsp70, and STAT-2, and inducs p38/MAPK xpssion in a postat canc cll lin (16) . Ashwagandha may inhibit tumgowth (1) (21) and incass cytotoxic T lymphocyt poduction (8) . In vitstudis hav shown that oot xtacts hav cytotoxic poptis against lung, colon, cntal nvous systm, and bast canc cll lins (6) . Withain A inducs activ oxygn spcis (OS) gnation and disuption mitochondial unction in a human lukmia cll lin, thby inducing apoptosis (18) . In stogn cpto-positiv (+) and ngativ (-) bast canc clls, withain A inducs apoptosis and dcasd tumsiz (19) . Apoptosis canc clls by withanon is mdiatd though p53 (7) . Withianon alsxts anticanc activity by binding tth TPX2-Auoa A Complx (29) . Oth studis show ashwagandha’s cytotoxicity is latd tits stuctu; it nhancs ATPas and inhibits succinat dhydognas activitis, impaiing oxidativ phosphoylation.
Its botanical nam is Withania somnia , and it’s alsknown by sval oth nams, including Indian ginsng and wint chy.
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major ingredient ashwagandha.