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Tamoxifen syrupSoltamoxcontains a type of sugar called lactoseIf you have been told by a doctor that you cannot digest lactoselactose intolerantor other sugarstalk to your doctor before taking this drug.

Some side effects can be seriousIf you experience any of the following symptomscontact your doctor immediatelyor call 911Vision problems Loss of appetite Swelling and pain in calf Chest pain Coughing up blood Yellowing of the skin or eyes Unusual bruising or bleeding Fever Blisters Rash Swelling of the eyesfacelipstonguethroathandsarmsfeetanklesor lower legs Wheezing or shortness of breath New breast masses Muscle weakness Restlessness.

Tamoxifen can increase your chances of getting a blood clotLet your doctor or nurse know if you have ever had a blood clot or deep vein thrombosisDVT

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there is evidence of an increased incidence of thromboembolic events, including deep-vein thrombosis and pulmonary embolism, during tamoxifen therapy.

However, the risk of endometrial cancer is still low among women on tamoxifen approximately 2 out of 1000 women on tamoxifen will develop endometrial cancer.

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The drug may also be prescribed for off-label usessuch as treating certain brain cancers and McCune-Albright syndromea genetic disorder that can cause early puberty in girls.

Talk to your doctor about these risksand notify him if you have any unusual problems while taking this medication.

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ATamoxifen is a medication that is used to treat or prevent breast cancerTamoxifen is in the group of medications called selective estrogen receptor modulator or SERMsTamoxifen interferes with the activity of estrogenthat may promote the growth of breast cancerSome breast cancers are classified as estrogen receptor positive which means they have a protein that estrogen binds toThese breast cancers depend on estrogen to grow and tamoxifen works against the effects of estrogen on these cellsThe prescribing information on tamoxifen lists the following as the most common side effects of the medicationhot flashesheadachesfatiguenausea/vomitingvaginal drynessand skin rashThe side effects are similar to those experienced during menopauseThe prescribing information on tamoxifen states that depending on your type of breast cancer the treatment length will varyPatients with metastatic breast cancer may take tamoxifen for long periods of time depending on the cancer’s response to the medicationWhen used in patients with early stage breast cancertamoxifen is generally prescribed for 5 yearsTamoxifen has been linked to endometrial cancer is some womenand the length of time taking the medication increases the riskPatients who do not have a uterus are not at riskThis is one of the main reasons that tamoxifen is not taken for longer than 5 yearsCataracts are a common eye issue as we agebut it is found that tamoxifen can increase the risk of developing this conditionIf you are taking chemotherapy medications while taking tamoxifenthere is a small increase in the risk for developing blood clotsThe total number of women who experienced this side effect was very smallThe risk is similar to taking estrogen hormone replacement therapyLori PoulinPharmD.

AThere are numerous drugs that have possible interactions with tamoxifenThe following is a list of some of the medications that can interact with tamoxifenBlood thinnersCoumadinwarfarinHIV/AIDS medicationsRescriptorNorvirheart rhythm medicationsamiodarone or quinidineantidepressantsWellbutrinCymbaltaProzacimipraminePaxilZoloftKeep in mind that this list is not complete and there are other interactions that may occurIt is always good to check with your doctor or pharmacist about specific medications you may be concerned withso that you can get a more specific answerMegan UeharaPharmD.

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The prescribing information on tamoxifen lists the following as the most common side effects of the medication hot flashes, headaches, fatigue, nausea vomiting, vaginal dryness, and skin rash.

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