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The improvement in radiological findings such as joint spacesubarticular sclerosissynovial effusionarticular erosion and osteophytes was due to the anti-inflammatory activity of Bserrata resinIt soothes the joints and also helps treat levels of synovial fluidmaking the entire structure lubricated and easy to rotate or to moveAKBA helps preserve structural integrity of the joint cartilage and maintains a healthy immune mediator cascade at a cellular levelShallaki is mediated through the vascular phenomenonit improves blood supply to joints and restores integrity of vessels obliterated by spasm of internal damage13Decrease in biochemical parametersmainlyCRPserum triglycerides and erythrocyte sedimentation rateESRis due to anti-inflammatory activity.
OsteoarthritisOAis the most common form of arthritiswhich is degenerative in natureIt is characterized by progressive disintegration of articular cartilageformation of new bone in the floor of the cartilage lesionseburnationand at the joint marginsosteophytesand leads to chronic disability at older ages1Clinical manifestations of OA range from mild to severeand affect the joints in hands and weight bearing joints such as kneeshipsfeet and spineOA is a clinical syndrome characterized by joint paintendernesslimitation of movementscrepitusoccasional effusion and variable degrees of inflammation without systemic effects2According to epidemiologythe prevalence of OA in India is 22-39Radiographic evidence of OA is present in majority of people over age 65among them80people are over 75 yearsApproximately11of those over 65 have symptomatic OA of the kneeIn India5.3males and 4.8females are aged more than 65 years3OA strikes women more often than men and it increases in prevalenceincidence and severity after menopauseThe etiology of OA is multifactorialVarious morphological as well as biochemical changes result in a softenedulcerated and malfunctioning articular cartilage4It has been postulated that agegenderbody weightrepetitive trauma and genetic factors are the risk factors which play an important role in the manifestation of OA5]
Joint pain and inflammation due to osteoarthritisChronic back and muscular painJoint pain after menopause.
Each tablet containsShallakiBoswellia serrataole-gum resin extract125 mg.
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