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Along with its needed effectsa medicine may cause some unwanted effectsAlthough not all of these side effects may occurif they do occur they may need medical attention.

Weight gainLogistic regression analysis has shown a positive dose response for weight gainFive to 10of adult patients experienced a weight gain of 7or greatervsup to 5in placeboAmong children and adolescentsa weight gain of 7or greater occurred in 7to 21of patients receiving this drug compared with up to 7in placebo patientsMean change in body weight was 1.7 to 2 kg in 3 to 6 week trials and 4.4 kg in 26 week trialsThese results were not adjusted for normal growthRef]

Common1to 10Shifts in thyroid hormones and TSHhyperprolactinemiaaltered hormone levelshypothyroidism.

This medicine may cause tardive dyskinesiaa movement disorderCheck with your doctor right away if you have lip smacking or puckeringpuffing of the cheeksrapid or worm-like movements of the tongueuncontrolled chewing movementsor uncontrolled movements of the arms and legs.

Common1to 10Hypertoniaincoordinationtremorspeech disorderataxialethargyparesthesiaextrapyramidal disorderbalance disorderhypoesthesiarestless leg syndromehypersomniatremor.

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NoteThis document contains side effect information about quetiapineSome of the dosage forms listed on this page may not apply to the brand name Seroquel.

Very common10or moreDiscontinuation syndrome12.1agitationup to 20

DyslipidemiaAcross indicationsadult patients who experienced shifts in total cholesteroltriglyceridesLDL-cholesteroland HDL-cholesterol from baseline to clinically significant levels occurred in up to 18226and 14of patients receiving this drug compared with up to 7165and 14receiving placeborespectivelyFor pediatric patientsthe shifts were up to 12228and 15compared to up to 3135and 19for this drug and placeborespectively.

Uncommon0.1to 1Abnormal dreamsabnormal thinkingamnesiapsychosishallucinationsmanic reactiondepersonalizationcatatonic reaction.

Do not suddenly stop taking this medicine without checking first with your doctorYour doctor may want you to gradually reduce the amount you are using before stopping it completelyThis will decrease the chance of having withdrawal symptoms such as nauseavomitinginsomniadizzinessirritabilityor headache.

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Potential for cognitive and motor impairment since seroquel xr has the potential to impair judgment, thinking, or motor skills, patients should be cautioned about performing activities requiring mental alertness, such as operating a motor vehicle or operating hazardous machinery, until they are reasonably certain that seroquel xr therapy does not affect them adversely.

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