Prozac, or fluoxetine, also called sarafem and fontex, is a selective serotonin reuptake inhibitor ssri , and the most common side effects are gastrintestinal, such as nausea and loss of appetite anorexia , and most of the serotonin in the human body is produced and utilized in the nervous system of the gut.
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Patients on stable doses of phenytoin and carbamazepine have developed elevated plasma anticonvulsant concentrations and clinical anticonvulsant toxicity following initiation of concomitant fluoxetine treatment.
The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongationBefore using fluoxetinetell your doctor or pharmacist of all the drugs you take and if you have any of the following conditionscertain heart problemsheart failureslow heartbeatQT prolongation in the EKGfamily history of certain heart problemsQT prolongation in the EKGsudden cardiac death
All patients being treated with antidepressants for any indication should be monitored appropriately and observed closely for clinical worseningsuicidalityand unusual changes in behaviorespecially during the initial few months of a course of drug therapyor at times of dos e changeseither increases or decreases
In US placebo-controlled clinical trials of fluoxetine for other approved indicationsanxietynervousnessand insomnia have been among the most commonly reported adverse reactionssee Table 6 and ADVERSE REACTIONS
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