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Restless Leg SyndromeModerate renal impairmentCrCl 30 to 50 mL/minNo dosage adjustment is necessary Severe renal impairment without regular dialysisNo data available.

LevodopaciprofloxacinCiprofluvoxamineLuvoxmetoclopramideReglanomeprazolePriloseca medication used to treat nausea and vomiting or mental illnesssuch as chlorpromazineThorazinefluphenazineProlixinmesoridazineSerentilperphenazineTrilafonthioridazineMellarilpromazineSparinetrifluoperazineStelazinethiothixeneNavaneor haloperidolHaldolor an estrogen such as PremarinPremproEstratestOgenEstradermClimaraVivelleestradioland others.

Other medications can affect the removal of ropinirole from your bodywhich may affect how ropinirole worksExamples include cimetidinefluvoxaminemexiletineomeprazolerifampinamong others.

Uncommon0.1to 1Sudden onset of sleepexcessive daytime somnolence.

The recommended adult starting dose for RLS is 0.25 mg once daily 1 to 3 hours before bedtimeAfter 2 daysif necessarythe dose can be increased to 0.5 mg once dailyand to 1 mg once daily at the end of the first week of dosingthen as shown in Table 2 as needed to achieve efficacyTitration should be based on individual patient therapeutic response and tolerabilityup to a maximum recommended dose of 4 mg dailyFor RLSthe safety and effectiveness of doses greater than 4 mg once daily have not been established.

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CommentsIf significant interruption in therapy occursretitration may be necessaryupon discontinuationthis drug should be gradually tapered over a 7-day periodThe extended-release tablet is designed to release medication over a 24-hour periodif rapid gastrointestinal transit occursand tablet residue is observed in the stoolthere is a risk of incomplete release of medication,

Restless Leg SyndromeModerate renal impairmentCrCl 30 to 50 mL/minNo dosage adjustment is necessary Severe renal impairment without regular dialysisNo data available.

Use this medication regularly in order to get the most benefit from itTo help you rememberuse it at the same time(seach dayTake this medication as prescribedDo not increase your dose or take it more often than directed.

FDA pregnancy category CIt is not known whether ropinirole is harmful to an unborn babyBefore taking this medicationtell your doctor if you are pregnant or plan to become pregnant during treatment.

Some side effects of ropinirole may occur that usually do not need medical attentionThese side effects may go away during treatment as your body adjusts to the medicineAlsoyour health care professional may be able to tell you about ways to prevent or reduce some of these side effectsCheck with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

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