Sevelamer hydrochloride is the active ingredient in kidney treatment renagel , which was first approved for.

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Gastrointestinal events are the most common adverse reactions reported with this drugBased on studies of 8 to 52 weeksthe most common reason for drug withdrawal are gastrointestinal adverse reactions3to 16Ref]

Renagel is used to control hyperphosphataemiahigh blood phosphate levelsin adults on dialysisa blood clearance technique used in patients with kidney diseaseIt can be used in patients undergoing haemodialysisdialysis using a blood filtration machineor peritoneal dialysiswhere fluid is pumped into the abdomen and an internal body membrane filters the bloodRenagel should be used with other treatments such as calcium or vitamin-D supplements to control the development of bone disease.

Bloodyblackor tarry stools heartburn indigestion nausea severe abdominal or stomach paincrampingor burning severe constipation severe vomiting trouble with breathing vomiting vomiting of material that looks like coffee groundssevere and continuing.

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therefore, any other medication should be taken at a gap of thirty minutes while using renagel.

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Table 2Starting Dose for Dialysis Patients Switching From Calcium Acetate to Renagel.

Renagel is indicated for the control of hyperphosphataemia in adult patients receiving haemodialysis or peritoneal dialysisRenagel should be used within the context of a multiple therapeutic approachwhich could include calcium supplements1,25-dihydroxy Vitamin D 3 or one of its analogues to control the development of renal bone disease.

Rememberkeep this and all other medicines out of the reach of childrennever share your medicines with othersand use only for the indication prescribed.

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A mass balance study using 14 c-sevelamer hydrochloride, in 16 healthy male and female volunteers showed that renagel hydrochloride is not systemically absorbed.

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