Do not use this medication if you have severe asthma, emphysema, or other breathing problem, or if you are allergic to promethazine or other phenothiazines such as chlorpromazine thorazine , fluphenazine permitil , perphenazine trilafon , prochlorperazine compazine, compro , thioridazine mellaril , or trifluoperazine stelazine .

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Administration of promethazine HClpromethazine hydrochloridehas been associated with reported cholestatic jaundice.

Get emergency medical help if you have any signs of an allergic reactionhivesdifficult breathingswelling of your facelipstongueor throat.

CardiovascularIncreased or decreased blood pressuretachycardiabradycardiafaintness.

The black box warning now clearly reads that promethazine hydrochloride injections should not be used in pediatric patients less than 2 years of age because of the potential for fatal respiratory depressionIt also advises caution should be exercised when administering the drug in the form of an injection to patients 2 and older.

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promethazine hydrochloride oral solution should not be used in pediatric patients less than 2 years of age because of the potential for fatal respiratory depression.

Lean is another name for purple drank, the special drug cocktail sipping syrup that combines codeine-based cough syrup with promethazine, lemon-lime soda, ice, and crushed up hard candies.

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Promethazine may cause other side effectsCall your doctor if you experience any unusual problems while you are taking this medication.

CardiovascularIncreased or decreased blood pressuretachycardiabradycardiafaintness.

If the suppository feels softhold it under coldrunning water for 1 minuteRemove the wrapperDip the tip of the suppository in waterLie down on your left side and raise your right knee to your chestA left-handed person should lie on the right side and raise the left kneeUsing your fingerinsert the suppository into the rectumabout 1/2 to 1 inch1.25 to 2.5 centimetersin children who are 2 years of age older and 1 inch2.5 centimetersin adultsHold it in place for a few momentsStand up after about 15 minutesWash your hands thoroughly and resume your normal activities.

Oral25 mg at bedtimeAlternatively12.5 mg may be administered before the evening meal and again at bedtime for antihistamine effects.

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Perennial and seasonal allergic rhinitisVasomotor rhinitisAllergic conjunctivitis due to inhalant allergens and foodsMilduncomplicated allergic skin manifestations of urticaria and angioedemaAmelioration of allergic reactions to blood or plasmaDermographismAnaphylactic reactionsas adjunctive therapy to epinephrine and other standard measuresafter the acute manifestations have been controlledPreoperativepostoperativeor obstetric sedationPrevention and control of nausea and vomiting associated with certain types of anesthesia and surgeryTherapy adjunctive to meperidine or other analgesics for control of postoperative painSedation in both children and adultsas well as relief of apprehension and production of light sleep from which the patient can be easily arousedActive and prophylactic treatment of motion sicknessAntiemetic therapy in postoperative patients.

The dosage is based on your agemedical conditionand response to treatmentIn childrenthe dosage may also be based on weightDo not increase your dose or take this medication more often than directed.

A very serious allergic reaction to this drug is rareHoweverget medical help right away if you notice any symptoms of a serious allergic reactionincludingrashitching/swellingespecially of the face/tongue/throatsevere dizzinesstrouble breathing.

A very serious allergic reaction to this drug is rareHoweverget medical help right away if you notice any symptoms of a serious allergic reactionincludingrashitching/swellingespecially of the face/tongue/throatsevere dizzinesstrouble breathing.

You should not take this medicine if you are allergic to promethazine or to similar medicines such as chlorpromazinefluphenazinemesoridazineperphenazineprochlorperazinethioridazineor trifluperazine.

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