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DVisual field defectsPericentral or paracentral scotomacentral scotoma with decreased visual acuityrarely field constrictionabnormal color vision.

Retinopathy appears to be dose related and has occurred within several monthsrarelyto several years of daily therapya small number of cases have been reported several years after antimalarial drug therapy was discontinuedIt has not been noted during prolonged use of weekly doses of the 4aminoquinoline compounds for suppression of malaria.

All patients on long-term therapy with this preparation should be questioned and examined periodicallyincluding the testing of knee and ankle reflexesto detect any evidence of muscular weaknessIf weakness occursdiscontinue the drug.

PLAQUENIL is not effective against chloroquine-resistant strains of Pfalciparum.

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plaquenil is associated with potential side effects, one of which is particularly worrisome to people who are prescribed the drug.

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Although most of the side effects listed below don’t happen very oftenthey could lead to serious problems if you do not check with your doctor or seek medical attention.

Use this medication regularly in order to get the most benefit from itIf you are taking it on a daily scheduletake it at the same time each dayTake this medication exactly as prescribedDo not stop taking it without talking with your doctorespecially if you are taking it for malariaIt is important to continue taking this for the length of time prescribedStopping prevention or treatment too soon may lead to infection or a return of the infection.

Use of PLAQUENIL in patients with psoriasis may precipitate a severe attack of psoriasisWhen used in patients with porphyria the condition may be exacerbatedThe preparation should not be used in these conditions unless in the judgment of the physician the benefit to the patient outweighs the possible hazard.

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Some people taking this medication over long periods of time or at high doses have developed irreversible damage to the retina of the eyeStop taking hydroxychloroquine and call your doctor at once if you have trouble focusingif you see light streaks or flashes in your visionor if you notice any swelling or color changes in your eyes.

Many medications can cause side effectsA side effect is an unwanted response to a medication when it is taken in normal dosesSide effects can be mild or severetemporary or permanent.

Retinopathy with changes in pigmentation and visual field defects have been reportedIn its early formit appears reversible on discontinuation of hydroxychloroquineIf allowed to developthere may be a risk of progression even after treatment withdrawalCases of maculopathies and macular degeneration have been reported and may be irreversible.

Dizzinessheadacheand convulsions have been reported with this class of drugs.

One tablet of 200 mg of hydroxychloroquine sulfate is equivalent to 155 mg base.

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