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Paroxetine can pass into breast milk and may cause side effects in the nursing babyYou should not breast-feed while using this medicine.

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Concomitant use or within 14 days of MAOIs increases risk of serotonin syndrome Reactions to concomitant administration with MAOIs include tremormyoclonusdiaphoresisnauseavomitingflushingdizzinesshyperthermia with features resembling neuroleptic malignant syndromeseizuresrigidityautonomic instability with possible rapid fluctuations of vital signsand mental status changes that include extreme agitation progressing to delirium and coma Starting paroxetine in a patient who is being treated with linezolid or IV methylene blue is contraindicated because of an increased risk of serotonin syndrome If linezolid or IV methylene blue must be administereddiscontinue SSRI immediately and monitor for CNS toxicitymay resume 24 hr after last linezolid or methylene blue doseor after 2 weeks of monitoring5 weeks for fluoxetinewhichever comes first.

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DUse in LIFE-THREATENING emergencies when no safer drug availablePositive evidence of human fetal risk.

This information does not contain all possible interactions or adverse effectsThereforebefore using this producttell your doctor or pharmacist of all the products you useKeep a list of all your medications with youand share this information with your doctor and pharmacistCheck with your health care professional or doctor for additional medical adviceor if you have health questionsconcerns or for more information about this medicine.

This medication may be prescribed for other usesask your doctor or pharmacist for more information.

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the use of paroxetine or other ssris has been associated with the development of akathisia, which is characterized by an inner sense of restlessness and psychomotor agitation such as an inability to sit or stand still usually associated with subjective distress.

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20 mg PO qDay initiallymay increase by 10 mg qWeekup to 50 mg/day doses have been used but no increase in benefit seen at doses20 mg/day.

DurationAcute episodes of major depressive disorder require several months or longer of sustained pharmacologic therapysystemic evaluation has shown that efficacy was maintained for up to one year.

20 mg PO qDay initiallymay increase by 10 mg qWeeknot to exceed 60 mg/day.

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