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ACE inhibitor and thiazide therapy may impair glucose toleranceDosage adjustment of antidiabetic agentsincluding insulinmay be requiredIn diabetic patients treated with oral antidiabetic agents or insulinglycaemia levels should be closely monitored during the first month of treatment with an ACE inhibitorLatent diabetes mellitus may become manifest during thiazide therapy.
Thiazides should be used with caution in patients with impaired hepatic function or progressive liver diseasesince minor alterations of fluid and electrolyte balance may precipitate hepatic comasee section 4.3RarelyACE inhibitors have been associated with a syndrome that starts with cholestatic jaundice or hepatitis and progresses to fulminant necrosis andsometimesdeathThe mechanism of this syndrome is not understoodPatients receiving lisinopril/hydrochlorothiazide who develop jaundice or marked elevations of hepatic enzymes should discontinue lisinopril/hydrochlorothiazide and receive appropriate medical follow-up.
Keep taking Zestoretic for as long as your doctor tells you toit is a long term treatmentIt is important to keep taking Zestoretic every day.
This drug may make you dizzyAlcohol or marijuana can make you more dizzyDo not driveuse machineryor do anything that needs alertness until you can do it safelyLimit alcoholic beveragesTalk to your doctor if you are using marijuana.
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zestoretic hydrochlorothiazide lisinopril is a member of the ace inhibitors with thiazides drug class and is commonly used for heart failure and high blood pressure.
