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Talk to your doctor before taking this medicine if you are pregnantmight become pregnant or are breast-feeding.

Children may be more sensitive to the effects of this drugespecially effects on heart rate.

Kemadrinalong with other anticholinergic drugshas the potential to be abusedAlthough the cases of abuse are rarephysicians should exercise caution in prescribing Kemadrin to patients with symptoms that may not be genuine.

Kemadrin is contra-indicated in individuals with known hypersensitivity to any component of the preparationuntreated urinary retentionclosed angle glaucoma and gastro-intestinal obstruction.

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Kemadrin uses procyclidine is used to treat parkinsonism slowed movements, stiffness of the body, uncontrollable body movements, weakness, tiredness, soft voice, and other symptoms caused by damaged nerves in the brain .

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The recommended starting dose is half a tablet three times a dayThis can be increased by half a tablet each day until an effect is seenThe daily maintenance dose is usually two to six tabletsYour doctor may decide to stop your Kemadrin after three or four months to see if your side effects returnIf you need Kemadrin for a longer period of timeyour doctor may decide to stop every now and then.

Kemadrin should not be withdrawn abruptly as rebound parkinsonian symptoms may occur.

The safe use of this drug in pregnancy has not been establishedthereforethe use of procyclidine hydrochloride in pregnancylactationor in women of childbearing age requires that the potential benefits be weighed against the possible hazards to the mother and child.

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An antihistamine such as diphenhydramineBenadrylotherschlorpheniramineChlor-TrimetonotherstriprolidineActifedothersbrompheniramineDimetappothersclemastineTavistand othersantihistamines are often found in prescription and over-the-counter coldallergyand sleep medicines

To listen to or request a copy of this leaflet in Braillelarge print or audio please callfree of charge0800 198 5000UK only)

Anticholinergics can stop severe muscle spasms of the backneckand eyes that are sometimes caused by psychiatric drugsIt can also decrease other side effects such as muscle stiffness/rigidityextrapyramidal signs-EPSIt is not helpful in treating movement problems caused by tardive dyskinesia and may worsen them.

Kemadrin may be combined with levodopa or amantadine in patients who are inadequately controlled on a single agent.

In general younger patients or those with postencephalitic parkinsonism may require higher doses for a therapeutic response than older patients and those with arteriosclerotic parkinsonism.

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