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MICROZIDEhydrochlorothiazide capsuleis indicated in the management of hypertension either as the sole therapeutic agentor in combination with other antihypertensivesUnlike potassium sparing combination diuretic productsMICROZIDEhydrochlorothiazide capsulemay be used in those patients in whom the development of hyperkalemia cannot be riskedincluding patients taking ACE inhibitors.

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Taking these drugs with hydrochlorothiazide can cause further electrolyte lossespecially potassiumThis can lead to medical problemsExamples of these drugs include:

Eye painvision problemsdry mouththirstnauseavomitingfeeling weakdrowsyrestlessor light-headedfast or uneven heartbeatmuscle pain or weaknessnumbness or tingly feelinga redblisteringpeeling skin rash

This medicine is sometimes prescribed for other usesask your doctor or pharmacist for more information.

Calcium excretion is decreased by thiazidesand pathologic changes in the parathyroid glandswith hypercalcemia and hypophosphatemiahave been observed in a few patients on prolonged thiazide therapy.

CorticosteroidACTHintensified electrolyte depletionparticularly hypokalemia.

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The purpose of this study was to determine the stability of baclofen, captopril, diltiazem hydrochloride, dipyridamole, flecainide acetate, labetalol hydrochloride, metoprolol tartrate, verapamil hydrochloride and spironolactone hydrochlorothiazide in 1 mixtures of ora-sweet ora plus and ora-sweet sf ora plus.

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The adverse reactions associated with hydrochlorothiazide have been shown to be dose relatedIn controlled clinical trialsthe adverse events reported with doses of 12.5 mg hydrochlorothiazide once daily were comparable to placeboThe following adverse reactions have been reported for doses of hydrochlorothiazide 25 mg and greater andwithin each categoryare listed in the order of decreasing severity.

Address medical inquiries toWATSONMedical Communications P.OBox 1953MorristownNJ 07962-1953800-272-5525Manufactured ByWatson Pharma Private LimitedVernaSalcetteGoa 403 722 INDIADistributed ByWatson PharmaIncMorristownNJ 07962 USARevisedFebruary 2011.

Tell your doctor and pharmacist if you are allergic to hydrochlorothiazidesulfonamide antibiotic medicationspenicillinor any other drugstell your doctor and pharmacist what other prescription and nonprescription medicationsvitaminsnutritional supplementsand herbal products you are taking or plan to takeBe sure to mention any of the followingbarbiturates such as phenobarbital and secobarbitalSeconalcorticosteroids such as betamethasoneCelestonebudesonideEntocortcortisoneCortonedexamethasoneDecadronDexpakDexasoneothersfludrocortisoneFlorinefhydrocortisoneCortefHydrocortonemethylprednisoloneMedrolMeproloneothersprednisolonePreloneothersprednisoneDeltasoneMeticortenSterapredothersand triamcinoloneAristocortAzmacortcorticotropinACTHH.PActhar Gelinsulin and oral medications for diabeteslithiumEskalithLithobidmedications for high blood pressure or painnonsteroidal anti-inflammatory drugsNSAIDssuch as ibuprofenAdvilMotrinothersand naproxenAleveNaprosynothersYour doctor may need to change the doses of your medications or monitor you carefully for side effectsif you are taking cholestyramine or colestipoltake them 1 hour before or 4 hours after taking hydrochlorothiazidetell your doctor if you have kidney diseaseYour doctor may tell you not to take hydrochlorothiazidetell your doctor if you have or have ever had diabetesasthmagoutsystemic lupus erythematosusSLEa chronic inflammatory conditionhigh cholesterolor liver diseasetell your doctor if you are pregnantplan to become pregnantor are breastfeedingIf you become pregnant while taking hydrochlorothiazidecall your doctor immediatelyplan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothingsunglassesand sunscreenHydrochlorothiazide may make your skin sensitive to sunlightyou should know that hydrochlorothiazide may cause dizzinesslightheadednessand fainting when you get up too quickly from a lying positionThis is more common when you first start taking hydrochlorothiazideTo avoid this problemget out of bed slowlyresting your feet on the floor for a few minutes before standing upAlcohol can add to these side effects.

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