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In instances involving treatment of edema due to liver pathologiesLasix is used in the initial dose of 20-80 mgIn the case of acute renal failureLasix injections are recommendedInjections can be administered intramuscularly or intravenouslyDosage for each patient is selected individually depending on the severity of the pathological condition.

Lasix is dispensed in tablet formIt is available at a dosage strength of 40 mg with 45 tablets per pack.

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For treating edema in patients with cardiac insufficiencyLasix is prescribed at a dose of 20-50 mg per dayDepending on body reactionsLasix dosage can be adjustedDuring decongestant therapy for chronic kidney failure as well as for nephrotic syndromeLasix is used in the initial dose of 40-80 mg and is adjusted depending on patient body responseFor patients on hemodialysisthe daily dosage of Lasix is 250-1500 mg.

Angelantonio et al2014A role for intracellular zinc in glioma alteration of neuronal chloride equilibriumCell Death Dis 5 e1501 PMID25356870.

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Barbaro2017Dendritic cell amiloride-sensitive channels mediate sodium-induced inflammation and hypertensionCell Rep 21 1009 PMID29069584.

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Furosemide is primarily used for the treatment of hypertension and edemaIt is the first-line agent in most people with edema caused by congestive heart failureIt is also used for hepatic cirrhosisrenal impairmentnephrotic syndromein adjunct therapy for cerebral or pulmonary edema where rapid diuresis is requiredIV injectionand in the management of severe hypercalcemia in combination with adequate rehydration.

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Most centers do not utilize diuretics except on an as needed basis, since furosemide is only likely to be effective if given more than 4 hours after an il-2 dose.

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Loop diuretics, such as bumetanide and furosemide, inhibit the reabsorption of sodium and chloride ions in the ascending loop of henle within the kidneys nephrons.

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