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In addition, the beers expert panel considers digoxin to have questionable effects on the risk of hospitalization in patients with heart failure, and digoxin may be associated with increased mortality in older adults with heart failure.

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Seek emergency medical attention or call the Poison Help line at 1-800-222-1222An overdose of digoxin can be fatal.

Rememberkeep this and all other medicines out of the reach of childrennever share your medicines with othersand use this medication only for the indication prescribed.

Digoxin is usually taken once a dayTry to take this drug at the same time every dayFollow the label directions on how often to take itThe time allowed between doses and how long you need to take it will depend on your conditionYou may have to take this drug for a long timepossibly for the rest of your life.

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most of a dose of digoxin is excreted unchanged by the kidneys, although some of the dose is metabolised to pharmacologically active and inactive metabolites.

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Medication can help you control heart disease and high blood pressurebut it cannot cure it.

Drugs such as gentamicintetracyclineranolazineRanexaverapamilCalanVerelanVerelan PMIsoptinIsoptin SRCovera-HSquinidineQuinagluteQuinideamiodaroneCordaroneindomethacinIndocinIndocin-SRalprazolamXanaxXanax XRNiravamspironolactoneAldactoneand itraconazoleSporanoxcan increase digoxin levels and the risk of toxicityThe co-administration of digoxin and beta-blockersfor example propranololInderalInderal LAor calcium channel blockers or CCBsfor exampleverapamilwhich also reduce heart ratecan cause serious heart rate slowingDiuretic-inducedfor exampleby furosemideLasixreduction in blood potassium or magnesium levels may predispose patients to digoxin-induced abnormal heart rhythmsSaquinavirInviraseand ritonavirNorvirincrease the amount of digoxin in the body and may cause digoxin toxicityMirabegronMybetriqincreases digoxin blood levelsThe lowest dose of digoxin should be used if by people who are also using mirabegronOmeprazolePrilosecand other drugs that reduce stomach acidity may increase blood levels of digoxin.

Jay WMarksMDis a board-certified internist and gastroenterologistHe graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Talk to your healthcare provider about the most beneficial lifestyle goals for you.

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