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Cyclophosphamide TabletsUSP are white tablets with blue flecks containing 25 mg and 50 mg cyclophosphamiderespectively.

Metabolites interfere with malignant cell growth by cross-linking tumor cell DNAdrug does not have specificity for any phase of the cell cyclealso has potent immunosuppressive activity.

Take this medication by mouth exactly as directed by your doctorThe dosage is based on your medical conditionweightresponse to treatmentand other treatmentssuch as other chemotherapy drugsradiationyou may be receivingBe sure to tell your doctor and pharmacist about all the products you useincluding prescription drugsnonprescription drugsand herbal products

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How are patients typically monitoredPatients will usually have scheduled meetings with their healthcare provider while they are being treated with cyclophosphamideTypicallyblood will be drawn to check levels of blood cells and to monitor functions of some organ systemssuch as the kidneys or liverPatients may also undergo physical examinationsscans or other measures to assess side effects and response to therapy.

Before using this medicationtell your doctor or pharmacist your medical historyespecially ofliver diseasekidney diseasesurgery to remove your adrenal glands.

This is not a complete list of possible side effectsIf you notice other effects not listed abovecontact your doctor or pharmacist.

Leukopenia occurs in patients treated with cyclophosphamideis related to the dose of drugand can be used as a dosage guideLeukopenia of less than 2000 cells/mm 3 develops commonly in patients treated with an initial loading dose of the drugand less frequently in patients maintained on smaller dosesThe degree of neutropenia is particularly important because it correlates with a reduction in resistance to infectionsFever without documented infection has been reported in neutropenic patients.

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