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Taking colchicine with certain medications raises your risk of side effects from colchicineExamples of these drugs include:

Colchicine belongs to a class of drugs called anti-gout medicationsA class of drugs is a group of medications that work in a similar wayThese drugs are often used to treat similar conditions.

DisclaimerOur goal is to provide you with the most relevant and current informationHoweverbecause drugs interact differently in each personwe cannot guarantee that this information includes all possible interactionsThis information is not a substitute for medical adviceAlways speak with your healthcare provider about possible interactions with all prescription drugsvitaminsherbs and supplementsand over-the-counter drugs that you are taking.

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The dosage is based on your medical conditionother drugs/foods you may be takingand response to treatmentTo reduce your risk for serious side effectsdo not increase your dosetake it more frequentlyor take it for a longer time than directed by your doctorSerious side effects may occur even at usual prescribed doses.

DisclaimerOur goal is to provide you with the most relevant and current informationHoweverbecause drugs interact differently in each personwe cannot guarantee that this information includes all possible interactionsThis information is not a substitute for medical adviceAlways speak with your healthcare provider about possible interactions with all prescription drugsvitaminsherbs and supplementsand over-the-counter drugs that you are taking.

Advise patients that many drugs or other substances may interact with colchicine capsules and some interactions could be fatalThereforepatients should report to their healthcare provider all of the current medications they are takingand check with their healthcare provider before starting any new medicationsincluding short-term medications such as antibioticsPatients should also be advised to report the use of non-prescription medication or herbal productsGrapefruit and grapefruit juice may also interact and should not be consumed during treatment with colchicine capsules.

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Tell your doctor and pharmacist if you are allergic to colchicineany other medicationsor any of the ingredients in colchicine tabletsAsk your doctor or pharmacist or check the medication guide for a list of ingredientstell your doctor and pharmacist what prescription and nonprescription medicationsvitaminsnutritional productsand herbal supplements you are takinghave taken within the past 14 daysor plan to takeBe sure to mention any of the followingantibiotics such as azithromycinZithromaxclarithromycinBiaxinand erythromycinE.E.SE-MycintelithromycinKetekantifungals such as fluconazoleDiflucanitraconazoleSporanoxand ketoconazoleNizoralaprepitantEmendcholesterol-lowering medicationsstatinssuch as atorvastatinLipitorfluvastatinLescollovastatinMevacorpravastatinPravacholand simvastatinZocorcyclosporineGenGrafNeoralSandimmunedigoxinDigitekLanoxindiltiazemCardizemDilacorTiazacothersfibrates such as bezafibratefenofibrateAntaraLipofenand gemfibrozilLopidmedications for HIV or AIDS such as amprenavirAgeneraseatazanavirReyatazfosamprenavirLexivaindinavirCrixivannelfinavirViraceptritonavirin KaletraNorvirand saquinavirInvirasenefazodoneranolazineRanexaand verapamilCalanCoveraIsoptinVerelanYour doctor may need to change the doses of your medications or monitor you carefully for side effects tell your doctor if you have or have ever had kidneyor liver diseasetell your doctor if you are pregnantplan to become pregnantor are breast-feedingIf you become pregnant while taking colchicinecall your doctor.

Colchicine is used to treat the symptoms of gout or familial Mediterranean feverFamilial Mediterranean fever is passed down in familiesIt can cause inflammationpain and swellingin the jointslungsor abdomenstomach area

If you are taking this medication to prevent attacks of pain caused by familial Mediterranean feverthe usual dose is 1.2 to 2.4 milligrams dailyThe total dose may be taken once daily or divided into two doses a dayYour doctor may need to adjust your dose to control your symptoms or if you have side effects.

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