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Use of ARALEN in patients with psoriasis may precipitate a severe attack of psoriasisWhen used in patients with porphyria the condition may be exacerbatedThe drug should not be used in these conditions unless in the judgment of the physician the benefit to the patient outweighs the potential risks.

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Chloroquine may cause heart rhythm disorders in some patients caution should be taken when using chloroquine, if you were born with or have a family history of prolonged qt interval, if you have acquired qt prolongation seen on ecg, electrical recording of the heart , if you have heart disorders or have a history of heart attack myocardial infarction , if you have salt imbalance in the blood especially low level of potassium or magnesium, see section other medicines and your anti-malarial tablets .

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If there is any indicationpast or presentof abnormality in the visual acuityvisual fieldor retinal macular areassuch as pigmentary changesloss of foveal reflexor any visual symptomssuch as light flashes and streakswhich are not fully explainable by difficulties of accommodation or corneal opacitiesthe drug should be discontinued immediately and the patient closely observed for possible progressionRetinal changesand visual disturbancesmay progress even after cessation of therapy.

Because of the potential for serious adverse reactions in nursing infants from chloroquinea decision should be made whether to discontinue nursing or to discontinue the drugtaking into account the potential clinical benefit of the drug to the mother.

When prolonged therapy with any antimalarial compound is contemplatedinitialbase lineand periodic ophthalmologic examinationsincluding visual acuityexpert slit-lampfunduscopicand visual field testsshould be performed.

Keep all appointments with your doctor and the laboratoryYour doctor may order certain lab tests to check your response to chloroquine phosphateYour doctor will also test your reflexes to see if you have muscle weakness that may be caused by the drug.

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Intervention options can involvediazepam for life-threatening symptomsseizures and sedationepinephrine for treatment of vasodilation and myocardial depressionpotassium replacement with close monitoring of serum potassium levels.

Adults1 g600 mg basedaily for two daysfollowed by 500 mg300 mg basedaily for at least two to three weeksTreatment is usually combined with an effective intestinal amebicide.

If your symptoms or health problems do not get better or if they become worsecall your doctorDo not share your drugs with others and do not take anyone else’s drugsKeep a list of all your drugsprescriptionnatural productsvitaminsOTCwith youGive this list to your doctorTalk with the doctor before starting any new drugincluding prescription or OTCnatural productsor vitaminsSome drugs may have another patient information leafletCheck with your pharmacistIf you have any questions about chloroquineplease talk with your doctornursepharmacistor other health care providerIf you think there has been an overdosecall your poison control center or get medical care right awayBe ready to tell or show what was takenhow muchand when it happened.

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