If you are or will be breast-feeding while you use cefixime, check with your doctor or pharmacist.

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Comments Initial therapy for disseminated gonococcal infections requires parenteral therapy which should be continued for 24 to 48 hours after clinical improvement is observedOral therapy may then be administered to complete a total course of at least 1 weekDoxycycline therapy for 7 daysif not pregnantor single-dose azithromycin is also recommended to treat possible concurrent chlamydial infectionThe patient’s sexual partner(sshould also be evaluated/treated.

Several cephalosporins have been implicated in triggering seizuresparticularly in patients with renal impairment when the dosage was not reducedsee DOSAGE AND ADMINISTRATION and OVERDOSAGEIf seizures associated with drug therapy occurthe drug should be discontinuedAnticonvulsant therapy can be given if clinically indicated.

Different cefixime products are absorbed by the body in different ways and cannot be substituted for one anotherIf you need to switch from one cefixime product to anotheryour doctor may need to adjust your dose.

SUPRAX may be administered in the presence of impaired renal functionNormal dose and schedule may be employed in patients with creatinine clearances of 60 mL/min or greaterRefer to Table 2 for dose adjustments for adults with renal impairmentNeither hemodialysis nor peritoneal dialysis removes significant amounts of drug from the body.

Comments The CDC regimen is recommended as an alternative if ceftriaxone is not availableThe patient’s sexual partner(sshould also be evaluated/treated.

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cefixime is contraindicated in individuals who are hypersensitive to the drug or other cephalosporins and should be used with caution in individuals who are hypersensitive to penicillins.

Although specific information is unavailable, concomitant administration of probenecid reportedly increases peak serum concentrations and the area under the serum concentration-time curve auc of cefixime and decreases renal clearance and volume of distribution of the drug.

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Prescribing Supraxcefiximein the absence of a proven or strongly suspected bacterial infection is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.

Strep throat is a bacterial infection of the throatSigns and symptoms of strep throat include headachenauseavomitingsore throatand fever.

Staphylococcus or staph is a group of bacteria that can cause a multitude of diseasesStaph infections can cause illness directly by infection or indirectly by the toxins they produceSymptoms and signs of a staph infection include rednessswellingpainand drainage of pusMinor skin infections are treated with an antibiotic ointmentwhile more serious infections are treated with intravenous antibiotics.

SUPRAX is indicated in the treatment of adults and pediatric patients six months of age or older with pharyngitis and tonsillitis caused by susceptible isolates of Streptococcus pyogenesNotePenicillin is the usual drug of choice in the treatment of Streptococcus pyogenes infectionsSUPRAX is generally effective in the eradication of Streptococcus pyogenes from the nasopharynxhoweverdata establishing the efficacy of SUPRAX in the subsequent prevention of rheumatic fever is not available

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Cefixime for oral suspension is a cephalosporin antibacterial drug indicated in the treatment of adults and pediatric patients six months of age or older with the following infections when caused by susceptible isolates of the designated bacteria .

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