The overall response rate of streptococcus pneumoniae to cefixime trihydrate was approximately 10 lower and that of haemophilus influenzae or moraxella catarrhalis approximately 7 higher 12 when beta-lactamase positive isolates of h.

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Tell your doctor and pharmacist if you are allergic to cefiximeother cephalosporin antibiotic such as cefaclorCeclorcefadroxil cefazolinAncefKefzolcefdinircefditorenSpectracefcefepimeMaxipimecefotaximeClaforancefotetancefoxitinMefoxincefpodoximecefprozilceftarolineTeflaroceftazidimeFortazTazicefin AvycazceftibutenCedaxceftriaxoneRocephincefuroximeZinacefor cephalexinKeflexpenicillin antibioticsor any other medicationstell your doctor and pharmacist what prescription and nonprescription medicationsvitaminsnutritional supplementsand herbal products you are takingor plant to takeBe sure to mention any of the followinganticoagulantsblood thinnerssuch as warfarinCoumadinJantovenand carbamazepineCarbatrolEpitoEquetroTegretolTerilYour doctor may need to change the doses of your medications or monitor you carefully for side effectstell your doctor if you have or have ever had gastrointestinal diseaseGIaffecting the stomach or intestinesespecially colitiscondition that causes swelling in the lining of the colonlarge intestineor kidney or liver diseasetell your doctor if you are pregnantplan to become pregnantor are breastfeedingIf you become pregnant while taking cefiximecall your doctorif you have phenylketonuriaPKUan inherited condition in which a special diet must be followed to prevent mental retardationyou should know that cefixime chewable tablets are sweetened with aspartame that forms phenylalanine.

Gastric lavage may be indicatedotherwiseno specific antidote existsCefixime is not removed in significant quantities from the circulation by hemodialysis or peritoneal dialysisAdverse reactions in small numbers of healthy adult volunteers receiving single doses up to 2 g of cefixime did not differ from the profile seen in patients treated at the recommended doses.

Bacterial or fungal overgrowth of nonsusceptible organisms may occur with prolonged or repeated therapy.

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Several cephalosporins have been implicated in triggering seizuresparticularly in patients with renal impairment when the dosage was not reducedsee DOSAGE AND ADMINISTRATION and OVERDOSAGEIf seizures associated with drug therapy occurthe drug should be discontinuedAnticonvulsant therapy can be given if clinically indicated.

Cefixime has not been studied for use during labor and deliveryTreatment should only be given if clearly needed.

Dosage must be adjusted in severe renal insufficiencyhigh doses may cause CNS toxicityincluding seizuressuperinfections and promotion of nonsusceptible organisms may occur with prolonged use or repeated therapy.

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the rise of gonorrhea that is resistant to cefixime or ceftriaxone is concerning because such strains of gonorrhea are usually resistant to other commonly used antibiotics, including a class called quinolones a widely used quinolone is ciprofloxacin cipro, penicillins, tetracyclines and azithromycin zithromax.

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Take this medication by mouth with or without food as directed by your doctorusually once a dayIn childrenthis medication may also be taken twice a dayevery 12 hoursIf you are taking the chewable tabletschew thoroughly and then swallow.

About 4050absorbed orally whether administered with or without foodhowevertime to maximal absorption is increased approximately 0.8 hours when administered with food.

Pregnancy Category BReproduction studies have been performed in mice and rats at doses up to 40 times the human dose and have revealed no evidence of harm to the fetus due to cefiximeThere are no adequate and well-controlled studies in pregnant womenBecause animal reproduction studies are not always predictive of human responsethis drug should be used during pregnancy only if clearly needed.

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