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Cefadroxil should be used with caution in patients with renal disease or renal impairment because the drug is eliminated via renal mechanisms.

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Beta-hemolytic streptococci Staphylococciincluding penicillinase-producing strains StreptococcusDiplococcuspneumoniae Escherichia coli Proteus mirabilis Klebsiella species MoraxellaBranhamellacatarrhalis.

Inhaled antiinfectives are classified here based on the fact that preparations for inhalation can not be separated from preparations for injection.

Several cephalosporins have been implicated in triggering seizuresparticularly in patients with renal impairmentwhen the dosage was not reducedsee DOSAGE AND ADMINISTRATION and OVERDOSAGEIf seizures associated with drug therapy occurthe drug should be discontinuedAnticonvulsant therapy can be given if clinically indicated.

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In addition to the adverse reactions listed above which have been observed in patients treated with cefadroxilthe following adverse reactions and altered laboratory tests have been reported for cephalosporin-class antibiotics:

Hematologic side effects have included moderate transient neutropeniaagranulocytosisand thrombocytopeniaCephalosporin-class antibiotics have been associated with aplastic anemiahemolytic anemiahemorrhageprolonged prothrombin timepositive Coombstesteosinophiliaand pancytopeniaRef]

Prolonged use of DURICEFcefadroxilmay result in the overgrowth of honsusceptible organismsCareful observation of the patient is essentialIf superinfection occurs during therapyappropriate measures should be taken.

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These are not all of the side effects that may occurIf you have questions about side effectscall your doctorCall your doctor for medical advice about side effects.

Diarrhea that is watery or bloodyfeverchillsbody achesflu symptomsunusual bleeding or bruisingseizureconvulsionspale or yellowed skindark colored urinefeverconfusion or weaknessjaundiceyellowing of the skin or eyesfeverswollen glandsrash or itchingjoint pain.

HematologicNeutropenialeukopeniaeosinophiliathrombocytopeniathrombocytosisimpaired platelet aggregation.

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