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No statistically significant differences in the pharmacokinetics of bupropion were observed in patients with mild to moderate hepatic cirrhosis compared with healthy volunteers, but bupropion plasma levels showed a higher variability between individual patients.

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psychotherapy and, if necessary, antidepressant medication such as bupropion wellbutrin and generics , citalopram celexa and generics , and fluoxetine prozac and generics , can often help.

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