More recent studies have demonstrated that amantadine is a weak, non-competitive nmda receptor antagonist k 1 10 m .

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Tliv dy mouth, suck (sugalss) had candy ic chips, chw (sugalss) gum, dink wat, us a saliva substitut.

Amantadin oal capsul dosn’t caus dowsinss, but it can caus oth sid cts.

In th U, indications inlunza A tatmnt vay btwn th mmb stats (i.., indicatd tatmnt and/pophylaxis adults; adults and childn; only adults and adolscnts). Plas chck th pscibing inomation.

Duing pgnancy, this mdication should b usd only whn claly ndd. Discuss th isks and bnits with you docto.

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food and drug administration fda has accepted for review the new drug application nda for ads-5102 amantadine hydrochloride extended-release capsules, for the treatment of levodopa-induced dyskinesia lid in patients with parkinson s disease.

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Tak this mdication by mouth with without ood as dictd by you docto, usually onc daily. Ask you doctphamacist whn ttak you mdication sinc dint bands a takn at dint tims (ith in th moning, at bdtim). Swallow this mdication whol. Dnot cush, chw, split th capsuls/tablts. Doing scan las all th dug at onc, incasing th isk sid cts.

Amantadin should b continud at last 10 days ollowing known xposu. Whn pophylaxis is statd with inactivatd inlunza A vius vaccin, it should b administd 2 t4 wks at th vaccin has bn givn (i.., until potctiv antibody sponss dvlop). Whn inactivatd inlunza A vius vaccin is unavailabl containdicatd, amantadin should b administd th duation known inlunza A inction in th community bcaus patd and unknown xposu.

Acut toxicity may b attibutabl tth anticholingic cts amantadin. Dug ovdos has thsultd in cadiac, spiatoy, nal cntal nvous systm toxicity. Th is nspciic antidot. minomation, plas chck th pscibing inomation ( Symmtl 2003 ).

Lss quntly (1-5 %) potd advs actions a: dpssion, anxity and iitability, hallucinations, conusion, anoxia, dy mouth, constipation, ataxia, livdticulais, piphal odma, othostatic hypotnsion, hadach, somnolnc, dam abnomality, agitation, dy nos, diahoa and atigu ( Symmtl 2003 ).

Dnot stop taking this mdication without consulting you docto. You condition may gt wos i this dug is suddnly stoppd i you dos is quickly dcasd. You doctmay gadually duc you dos tlssn th chanc symptoms such as agitation, anxity, hallucinations, dpssion, slud spch. Tll you doctight away any nw wosning symptoms.

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Although the mechanism of action is still not entirely understood, amantadine is thought to facilitate both da release and delay uptake from presynaptic neurones, while also upregulating and altering the conformation of post-synaptic receptors 2 .

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