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Raloxifene appears to act as an estrogen agonist in boneIt decreases bone resorption and bone turnoverincreases bone mineral densityBMDand decreases fracture incidencePreclinical data demonstrate that raloxifene is an estrogen antagonist in uterine and breast tissuesThese results are consistent with findings in clinical trialswhich suggest that EVISTA lacks estrogen-like effects on the uterus and breast tissue.
It is not known whether raloxifene passes into breast milk or if it could harm a nursing babyYou should not breast-feed while using this medicine.
Table 5EVISTA60 mg Once DailyRelated Increases in BMD for the Osteoporosis Treatment Study Expressed as Mean Percentage Increase vsPlacebo b,c.
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tell your doctor about all prescription, non-prescription, illegal, recreational, herbal, nutritional, or dietary drugs you re taking before taking evista, especially anticoagulants blood thinners such as coumadin warfarin colestid colestipol medications that contain estrogen such as hormone replacement therapy ert or hrt and lidoderm or xylocaine lidocaine proglycem diazoxide questran cholestyramine valium diazepam .