If indinavir is discontinued, allow a washout period of approximately 1 week before the temsirolimus dose is increased to the dose used before initiation of indinavir.
Information about Indinavir.
Increased levels of fatty substances called triglycerides increased levels of LDL-cholesterollow-density lipoproteinorbadcholesterol increased levels of sugarglucoseincreased levels of the hormone insulin decreased sensitivity to insulininsulin resistancedecreased levels of HDL-cholesterolhigh-density lipoproteinorgoodcholesterol.
Particular caution should be used when prescribing sildenafiltadalafilor vardenafil in patients receiving indinavirCoadministration of CRIXIVAN with these medications is expected to substantially increase plasma concentrations of sildenafiltadalafiland vardenafil and may result in an increase in adverse eventsincluding hypotensionvisual changesand priapismwhich have been associated with sildenafiltadalafiland vardenafilsee CONTRAINDICATIONS and PRECAUTIONSDRUG INTERACTIONS and PATIENT INFORMATIONand the manufacturer’s complete prescribing information for sildenafiltadalafilor vardenafil
Dieleman JPvan Rossum AMStricker BCet alPersistent leukocyturia and loss of renal function in a prospectively monitored cohort of HIV-infected patients treated with indinavirJournal of Acquired Immune Deficiency Syndromes 2003;32(2135-142.
Increased levels of fatty substances called triglycerides increased levels of LDL-cholesterollow-density lipoproteinorbadcholesterol increased levels of sugarglucoseincreased levels of the hormone insulin decreased sensitivity to insulininsulin resistancedecreased levels of HDL-cholesterolhigh-density lipoproteinorgoodcholesterol.
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