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40 mg orally every 12 hours initiallyincreasing every 3-7 daysmaintenance80-240 mg orally every 8-12 hoursnot to exceed 640 mg/day.
Swallow the extended-release capsules wholedo not splitchewor crush them.
Orally1 mg/kg/day divided q6hrafter 1 weekmay be increased by 1 mg/kg/day to maximum of 10-15 mg/kg/day if patientrefractoryallow 24 hours between dosing changes IntravenouslyIV0.01-0.2 mg/kg over 10 minutesnot to exceed 5 mg.
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