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COUMADIN is contraindicated in women who are pregnant except in pregnant women with mechanical heart valveswho are at high risk of thromboembolismsee WARNINGS AND PRECAUTIONS and Use In Specific PopulationsCOUMADIN can cause fetal harm when administered to a pregnant womanCOUMADIN exposure during pregnancy causes a recognized pattern of major congenital malformationswarfarin embryopathy and fetotoxicityfatal fetal hemorrhageand an increased risk of spontaneous abortion and fetal mortalityIf COUMADIN is used during pregnancy or if the patient becomes pregnant while taking this drugthe patient should be apprised of the potential hazard to a fetussee Use In Specific Populations
As heparin may affect the INRpatients receiving both heparin and COUMADIN should have INR monitoring at least:
These are not all of the side effects of COUMADINFor more informationask your healthcare provider or pharmacistCall your doctor for medical advice about side effectsYou may report side effects to FDA at 1800-FDA-1088.
VKORC1 and CYP2C9 gene variants generally explain the largest proportion of known variability in warfarin dose requirements.
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i have been on coumadin for years and i didn t know about all this food u can not eat while on bloodthinners wow and i have been eating and drinking a lot that your not alound to have,and i love mayo and i use a lot of it on my sandwishes.